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Anti-CEA / Carcinoembryonic Antigen Antibody (clone CLB-139) LS-C202068

Catalog Size Price
LS-C202068-1000 1000 µl Unavailable

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100% Guaranteed
Mouse Monoclonal [clone CLB-139] (IgG1) to Human CEA / Carcinoembryonic Antigen
Human
Immunofluorescence, Flow Cytometry
Unconjugated

Details

Human CEA / Carcinoembryonic Antigen
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [CLB-139]
Unconjugated
Affinity purified
Unmodified

Applications

  • Immunofluorescence
  • Flow Cytometry

Specificity and Use

Human granulocytes.
Directed against the CD66e-antigen, a 180-200 kD phosphoprotein, 90 kD PI-linked protein, which is expressed on mature human granulocytes. After activation of the granulocytes, expression the antigen is strongly increased. It reacts with 100% of mature human peripheral granulocytes. The monoclonal antibody reacts weakly with malignant cells of patients with B-cell derived chronic lymphoid leukemia (CLL). The monoclonal antibody does not react with normal human peripheral B-cells, T-cells, monocytes and platelets. In immunohistology the antibody reacts with a subpopulation of tissue macrophages and the Carcino Embryonic Antigen (CEA) expressed on colon carcinoma and other carcinomas.

Packaging

1% BSA, 20 mM Tris, 150 mM sodium chloride, pH 8.0, 0.001% Merthiolate
Store at 4°C.
For research use only.

About CEA / Carcinoembryonic Antigen

Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Therefore CEA is usually present only at very low levels in the blood of healthy adults. However, the serum levels are raised in some types of cancer, which means that it can be used as a tumor marker in clinical tests. Serum levels can also be elevated in heavy smokers.

Requested From: 
Date Requested: 6/25/2017

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