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CDKN2B / p15 INK4b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
| Gene Name: | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| Synonyms: | CDKN2B, CDK inhibitory protein, CDK4B inhibitor, INK4B, MTS2, Multiple tumor suppressor 2, p14_INK4B, p15, p14_CDK inhibitor, p15 CDK inhibitor, p15 INK4b, p15-INK4b, p15_INK4B, p14-INK4b, p15INK4b, CDK4I, MTS-2, TP15 |
| Target Sequences: | NM_004936 NP_004927.2 P42772 |
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CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa89-138) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa102-130) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CDKN2B / p15 INK4b Mouse anti-Human Monoclonal (OTI3B6) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CDKN2B / p15 INK4b Mouse anti-Human Monoclonal (Carrier-free) (OTI3B6) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Pig, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
CDKN2B / p15 INK4b Mouse anti-Human Monoclonal (OTI8H4) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CDKN2B / p15 INK4b Mouse anti-Human Monoclonal (Carrier-free) (OTI8H4) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CDKN2B / p15 INK4b Mouse anti-Human Monoclonal (OTI2D11) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CDKN2B / p15 INK4b Mouse anti-Human Monoclonal (Carrier-free) (OTI2D11) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa102-130) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa102-130) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa102-130) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa102-130) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa102-130) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa102-130) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CDKN2B / p15 INK4b Rabbit anti-Human Polyclonal (60-140 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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