LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
CDKN2A / p16INK4a Antibody (aa1‑30, APC) LS‑C207122
Antibody
P16INK4a antibody LS-C207122 is an APC-conjugated rabbit polyclonal antibody to human p16INK4a (CDKN2A). Validated for ELISA and WB.
Catalog
Size
Price
LS-C207122-200
200 µl
Unavailable

Popular CDKN2A / p16INK4a Products

Anti-p16INK4A antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B199 concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, IHC - Frozen
Anti-p16INK4A antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B647 dilution 1:500.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Anti-p16INK4A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1347 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Detection of p19ARF in MEF lysate (25 ug) using antibody (2 ug/ml).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Rat
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
Anti-p16INK4A antibody IHC of human colon, crypt. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5261 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

P16INK4a antibody LS-C207122 is an APC-conjugated rabbit polyclonal antibody to human p16INK4a (CDKN2A). Validated for ELISA and WB.
About CDKN2A / p16INK4a
Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. P42771 NM_000077 NP_000068.1

CDKN2A Antibody, ARF Antibody, Cdk4 inhibitor Antibody, CDK4 inhibitor p16-INK4 Antibody, INK4 Antibody, INK4A Antibody, Multiple tumor suppressor 1 Antibody, MTS-1 Antibody, MTS1 Antibody, p16-INK4 Antibody, p16-INK4A Antibody, p16INK4 Antibody, p19 Antibody, p14 Antibody, p16 Antibody, p16 INK4A Antibody, p16INK4A Antibody, p14ARF Antibody, TP16 Antibody, CDK4I Antibody, CDKN2 Antibody, CMM2 Antibody, MLM Antibody, p19ARF Antibody


Specifications

Target
Human CDKN2A / p16INK4a
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Allophycocyanin. Also available Unconjugated or conjugated with AP, FITC, PE, Biotin, HRP.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)
Epitope
aa1-30
Specificity
This hp16-INK4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human hp16-INK4A.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, no preservatives added
Storage
Short term: store at 4°C. Long term: aliquot and store -20°C for up to 6 months. Avoid freeze-thaw cycles. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Requested From: 
Date Requested: 6/22/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number