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Anti-CDKN1A / WAF1 / p21 Antibody LS-C44695

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CDKN1A / WAF1 / p21 Antibodies

Anti-CDKN1A / WAF1 / p21 Antibody (aa117-146) LS-C168621
Rabbit Polyclonal to Human CDKN1A / WAF1 / p21
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human CDKN1A / WAF1 / p21
Human
Western blot, Immunoprecipitation
Unconjugated

Details

Human CDKN1A / WAF1 / p21
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • Western blot (1:100 - 1:1000)
  • Immunoprecipitation

Specificity and Use

CDKN1A / WAF1 / p21 antibody was raised against human p21 protein.
Recognizes the human cyclin-dependent kinase inhibitor p21/WAF1, which is an important cell cycle regulatory protein, also known as CIP1. The p21 protein inhibits cell cycle progression at both the G1 and G2 checkpoints. The expression of p21 is inducible by a wide range of stress stimuli. Detects a band of approximately 21kD in MCF-7 cell lysates following UV radiation.
Immunohistology: This product does require antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH6.0 is recommended for this purpose.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About CDKN1A / WAF1 / p21

P38936 NM_078467 NP_000380.1

CDKN1A Antibody, CDKN1 Antibody, CIP1 Antibody, CDK-interacting protein 1 Antibody, DNA synthesis inhibitor Antibody, p21CIP1 Antibody, MDA6 Antibody, PIC1 Antibody, SDI1 Antibody, WAF1 Antibody, CAP20 Antibody, CDK-interaction protein 1 Antibody, MDA-6 Antibody, p21 Antibody

CDKN1A / WAF1 / p21 is a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli.

Western blot

Western blot
p21/WAF1 transfected cell lysate probed with Mouse anti-Human p21/WAF1 (LS-C44695).
 

Requested From: United States
Date Requested: 12/6/2016

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