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Anti-CDK6 Antibody LS-C6001

Ordering

Wt. Vol. Conc. Price
100 µg 1000 µl 0.1 mg/ml $435
Inquire for larger quantities

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Mouse Monoclonal (IgG1) to Human CDK6
Human
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

Details

Human CDK6
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein A purified

Applications

IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation

Specificity and Use

CDK6 antibody was raised against human recombinant full-length cdk6 polypeptide.
Antigen Recognized in Species Human. Reacts specifically with Cdk6 kinase, which can substitute for Cdk4. Cdk6 is highly expressed in some lymphoid tumor and sarcoma cell lines (ML-1 and U-2-OS resp.). Positive staining found in head and neck tumors.
Suitable for use in Immunohistochemistry (frozen sections and for paraffin-embedded tissue after microwave treatment), Western Blot and Immunoprecipitation. Immunohistochemistry: 1:10; Incubation Time 1-4 hr at RT or overnight at 2-8?C.

Packaging

Lyophilized, PBS, pH 7.4, 0.5% BSA, 0.09% sodium azide
1,000 µl Sterile ddH2O
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About CDK6

Q00534 NM_001259 NP_001250.1

CDK6 Antibody, CDKN6 Antibody, Cell division protein kinase 6 Antibody, Cyclin-dependent kinase 6 Antibody, Crk2 Antibody, PLSTIRE Antibody

Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle.

Requested From: United States
Date Requested: 9/29/2016

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