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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CDK4 Antibody (clone DCS‑35, Biotin) LS‑C88039
Antibody
CDK4 antibody LS-C88039 is a biotin-conjugated mouse monoclonal antibody to CDK4 from human, mouse, rat and other species. Validated for Func, IF, IP and WB.
Catalog
Size
Price
LS-C88039-0.1
0.1 ml
Unavailable
LS-C88039-0.5
0.5 ml
Unavailable
LS-C88039-1
1 ml
Unavailable

Popular CDK4 Products

Antibody
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot
Anti-CDK4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1970 dilution 1:50.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Antibody
Species: Human, Mouse, Rat
Applications: Immunofluorescence, Western blot, Immunoprecipitation
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Western blot analysis of extracts of various cell lines.
Species: Human, Mouse, Rat
Applications: Western blot

Product Description

CDK4 antibody LS-C88039 is a biotin-conjugated mouse monoclonal antibody to CDK4 from human, mouse, rat and other species. Validated for Func, IF, IP and WB.
About CDK4
Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. P11802 NM_000075 NP_000066.1

CDK4 Antibody, Cell division protein kinase 4 Antibody, Crk3 Antibody, Cyclin-dependent kinase 4 Antibody, CMM3 Antibody, p34/cdk4 Antibody, PSK-J3 Antibody


Specifications

Target
Human CDK4
Host
Mouse
Reactivity
Human, Mouse, Rat, Pig (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [DCS-35]
Conjugations
Biotin. Also available Unconjugated.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Immunofluorescence
  • Western blot (1 - 2 µg/ml)
  • Immunoprecipitation
  • Functional Assay
  • (applications tested for the base form of this product only)
Immunogen
CDK4 antibody was raised against purified recombinant cdk4 protein.
Specificity
aa 1-20
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
10mM PBS, pH 7.4, with 0.2% BSA and 0.09% Sodium Azide
Storage
Stable for 2 years when stored at 2-8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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