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Anti-CDK4 Antibody (C-Terminus) LS-C145969

Ordering

Wt. Vol. Conc. Price
50 µg - - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CDK4 Antibodies

Anti-CDK4 Antibody (C-Terminus) IHC-plus™ LS-B1970
Rabbit Polyclonal (IgG) to Mouse CDK4
Mouse, Human, Rat
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human CDK4
Human, Monkey, Rat, Dog, Rabbit
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human CDK4
Rabbit
Human, Monkey, Rat, Dog, Rabbit (tested or 100% immunogen sequence identity)
Pig (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

CDK4 antibody was raised against synthetic peptide from C-Terminus of human CDK4 (P11802, NP_000066). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%); Pig (91%); Galago (90%); Dog, Panda, Rabbit, Horse, Guinea pig (83%); Rat (75%).
LS-E10544 - Lyophilized - 100 µg - $145.00
C-Terminus
Human CDK4

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CDK4

P11802 NM_000075 NP_000066.1

CDK4 Antibody, Cell division protein kinase 4 Antibody, Crk3 Antibody, Cyclin-dependent kinase 4 Antibody, CMM3 Antibody, p34/cdk4 Antibody, PSK-J3 Antibody

Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase.

Western blot

Western blot
CDK4 antibody LS-C145969 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/5/2016

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