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Anti-CDK4 Antibody (C-Terminus) IHC-plus™ LS-B1970

Note: This antibody replaces LS-C41178, LS-C78990, LS-C51689


Wt. Vol. Conc. Price
- 100 µl 0.2 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CDK4 Antibodies

Anti-CDK4 Antibody (C-Terminus) IHC-plus™ LS-B1970
Rabbit Polyclonal (IgG) to Mouse CDK4
Mouse, Human, Rat
IHC - Paraffin, Western blot, Immunoprecipitation
Immunohistochemistry Image

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Rabbit Polyclonal (IgG) to Mouse CDK4
Mouse, Human, Rat
IHC - Paraffin, Western blot, Immunoprecipitation


Mouse CDK4
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Affinity purified


  • IHC - Paraffin (1:50)
  • Western blot
  • Immunoprecipitation

Specificity and Use

CDK4 antibody was raised against synthetic peptide from mouse CDK4.
Peptide mapping to the carboxy terminus of mouse Cdk4
Immunohistochemistry: LS-B1970 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1970 was determined to be 1:50.


Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% gelatin.
Store undiluted at 4 degrees C. Do not freeze.
For research use only.

About CDK4

P11802 NM_000075 NP_000066.1

CDK4 Antibody, Cell division protein kinase 4 Antibody, Crk3 Antibody, Cyclin-dependent kinase 4 Antibody, CMM3 Antibody, p34/cdk4 Antibody, PSK-J3 Antibody

Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase.


Anti-CDK4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1970 dilution 1:50.

Western blot

Western blot
Western blot of extracts from HeLa cells, using anti-Cdk4, Poly6333.

Requested From: United States
Date Requested: 10/26/2016

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