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Anti-CDK2 Antibody (phospho-Thr14) LS-C97133

Catalog	Size	Price
LS-C97133-400	400 µl	Unavailable

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Details

Target:	Human CDK2
Host:	Rabbit
Reactivity:	Human (tested or 100% immunogen sequence identity)
Predicted:	Mouse, Rat, Hamster, Xenopus, Cow (at least 90% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Protein A purified
Modifications:	Unmodified

Applications

Approved:

Dot Blot (1:500)

Specificity and Use

Blocking Peptide:

LS-E7438 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C97133. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

pThr14

Specificity:

This CDK2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T14 of human CDK2.

Packaging

Presentation:	PBS, 0.09% sodium azide
Storage:	Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions:	For research use only.

About CDK2

Uniprot: P24941 NCBI: NM_001798 NP_001789.2

Synonyms: CDK2 Antibody, Cell division protein kinase 2 Antibody, CDC2-related protein kinase Antibody, p33 protein kinase Antibody, p33(CDK2) Antibody, CDKN2 Antibody, Cyclin-dependent kinase 2 Antibody

Description: Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1, B3, D, or E. Triggers duplication of centrosomes and DNA.

(More About CDK2)

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Dot Blot

Dot blot of anti-Phospho-CDK2-pT14 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Requested From:
Date Requested: 8/19/2017

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