Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CDH15 / M Cadherin is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells.
M-Cadherin/Cadherin-15 in C2C12 Mouse Cell Line. M-Cadherin/Cadherin-15 was detected in immersion fixed C2C12 mouse myoblast cell line using Sheep Anti-Human M-Cadherin/Cadherin-15
Detection of Human M Cadherin/Cadherin 15 by Western Blot. Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line. PVDF Membrane was probed with 1 ug/ml of Sheep Anti-Human M-Cadherin/Cadherin15Antigen Affinity-purified Polyclonal Antibody followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody. A specific band was detected for M Cadherin/Cadherin15 at approximately130 kD (as indicated). This experiment was conducted under reducing conditions.
Detection of M-Cadherin/ Cadherin-15 in C2C12 Mouse Cell Line by Flow Cytometry. C2C12 mouse myoblast cell line was stained with Sheep Anti-Human M-Cadherin/ Cadherin-15 Antigen Affinity-purified Polyclonal Antibody or control antibody, followed by NorthernLights 557-conjugated Anti-Sheep IgG Secondary Antibody.
Requested From: United States
Date Requested: 2/21/2017