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Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.
Gene Name: | cell division cycle associated 5 |
Synonyms: | CDCA5, p35, Sororin |
Target Sequences: | NM_080668 NP_542399.1 Q96FF9 |
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