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CDC25C

cell division cycle 25C

CDC25C, a CDC25 dual specificity protein phosphatase, has been shown to affect the regulation of cell cycle control, and specifically the G2/M progression, through interaction with cdc/cyclin kinases and proliferating cell nuclear antigen (PCNA). Unlike CDC25A and CDC25B, CDC25C does not seem to have oncogenic properties. CDC25C null mutant mice are viable, fertile, and do not display obvious abnomalities. CDC25C expression is regulated by chk1, 14-3-3 protein, p53 and BRCA1, among other proteins. CDC25C is located on chromosome 5p31 near a region that is deleted in some hematologic disorders.

Gene Name: cell division cycle 25C
Family/Subfamily: Protein Phosphatase , CDC25
Synonyms: CDC25C, CDC25, CDC25C phosphatase, CDC25Hu3, Cell division cycle 25C, Phosphotyrosine phosphatase, PPP1R60, M-phase inducer phosphatase 3, Mitosis inducer CDC25
Target Sequences: NM_001790 NP_001781.2 P30307

Publications (2)

1
XJW20, a novel oxoindole derivative, induces G2/M arrest and apoptosis selectively in K562 leukemia cell line. Ye Z, Chen Z, Chen W, Xie J, Yang H, Lou Y, Yu Y. Chemico-biological interactions. 2010 183:133-41. (WB) [PubMed:19883635]
2
Ochratoxin A induces G(2) phase arrest in human gastric epithelium GES-1 cells in vitro. Cui J, Xing L, Li Z, Wu S, Wang J, Liu J, Wang J, Yan X, Zhang X. Toxicology letters. 2010 193:152-8. (WB) [PubMed:20060447]

☰ Filters
Antibodies (80)
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CDC25C (90)
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rabbit (60)
mouse (20)
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monoclonal mc (20)
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1535CT627.6.80 (1)
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233CT9.6.6 (6)
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pSer216 (8)
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160-240 aa (2)
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CDC25C Antibody - Immunohistochemical analysis of CDC25C (pS216) staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP-conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CDC25C Rabbit anti-Human Polyclonal (pSer216) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
CDC25C Antibody - Immunofluorescence analysis of U2OS cells.
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CDC25C Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CDC25C Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CDC25C Rabbit anti-Human Polyclonal (pSer216) Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CDC25C Antibody - Anti-CDC25C antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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CDC25C Mouse anti-Human Monoclonal (1F12) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CDC25C Antibody - Immunohistochemical analysis of CDC25C staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CDC25C Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
CDC25C Antibody - Immunoperoxidase of monoclonal antibody to CDC25C on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 6 ug/ml]
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CDC25C Mouse anti-Human Monoclonal (3B11) Antibody
Human
ELISA, IHC, IHC-P, IP, RNAi, WB
Unconjugated
100 µg/$423
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CDC25C Rabbit anti-Human Polyclonal (pThr48) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$689
CDC25C Antibody - 1:100 staining human brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CDC25C Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CDC25C Mouse anti-Human Monoclonal (Azide-free) Antibody
Human
IF, IHC, IP, WB
Unconjugated, Azide-free
100 µg/$1,151
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CDC25C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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CDC25C Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
Select
CDC25C Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
CDC25C Rabbit anti-Human Polyclonal (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Select
CDC25C Rabbit anti-Human Polyclonal (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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CDC25C Rabbit anti-Human Polyclonal (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
CDC25C Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDC25C Antibody. The picture on the right is blocked with the synthesized peptide.
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CDC25C Rabbit anti-Human Polyclonal (aa14-63) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
CDC25C Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CDC25C Antibody - Antibody staining MPIP3 in human testis sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH 6). Samples were incubated with primary antibody (1:25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
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CDC25C Mouse anti-Human Monoclonal (1535CT627.6.80) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
200 µl/$393
CDC25C Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CDC25C antibody.
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CDC25C Rabbit anti-Human Polyclonal (Ab-48) Antibody
Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
CDC25C Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CDC25C (Phospho-Ser216) Antibody. The picture on the right is blocked with the phospho peptide.
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CDC25C Rabbit anti-Human Polyclonal (pSer216) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CDC25C Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CDC25C Antibody. The picture on the right is blocked with the synthesized peptide.
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CDC25C Rabbit anti-Human Polyclonal (aa183-232) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CDC25C Antibody - Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using CDC25C (Phospho-Thr48) Antibody. The picture on the right is blocked with the phospho peptide.
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CDC25C Rabbit anti-Human Polyclonal (pThr48) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CDC25C Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded human Testis tissues with AEC staining using CDC25C Monoclonal Antibody.
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CDC25C Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
Select
CDC25C Rabbit anti-Human Polyclonal (30-110 aa) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
CDC25C Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µl/$440; 200 µl/$468
Viewing 1-25 of 90 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).