Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CDC14A, a homolog of the essential Saccharomyces cerevisiae cdc14 gene, is a member of the CDC14 subfamily. The gene product has been shown to dephosphorylate human Cdh1 and activate APC(Cdh1), the anaphase-promoting complex that ubiquitinates mitotic cyclins and allows cells to exit from mitosis. CDC14A also has been shown to interact with interphase centrosomes and to regulate the centrosome duplication cycle. At least three mRNA variants of CDC14A have been identified.