Mouse CD98

Rat

Mouse (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

H202-529.4.1.4

Unconjugated

Protein G purified

Unmodified

Thymic epithelial cells from mouse.

Recognizes murine CD98 (also known as 4F2 and SLC3A2), a type II transmembrane glycoprotein which associates with members of the L-type amino transporter family to form a heterodimeric complex. CD98 constitutes the heavy chain of the complex and is required for the surface expression and basolateral localization of the amino acid transporter complex in polarized epithelial cells. The CD98 heavy chain also interacts with beta 1 integrins and regulates their activation through the cytoplasmic domains and transmembrane regions. Studies suggest that overexpression of CD98 may contribute to cell growth and survival by regulating integrin signalling, and therefore may play an important role in tumorigenesis.

• Flow Cytometry (1:20 - 1:200)

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.