Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone H202-5184.108.40.206] (IgG1) to Mouse CD98
Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [H202-5220.127.116.11]
Protein G purified
Flow Cytometry (1:20 - 1:200)
Specificity and Use
CD98 antibody was raised against thymic epithelial cells from mouse.
Recognizes murine CD98 (also known as 4F2 and SLC3A2), a type II transmembrane glycoprotein which associates with members of the L-type amino transporter family to form a heterodimeric complex. CD98 constitutes the heavy chain of the complex and is required for the surface expression and basolateral localization of the amino acid transporter complex in polarized epithelial cells. The CD98 heavy chain also interacts with beta 1 integrins and regulates their activation through the cytoplasmic domains and transmembrane regions. Studies suggest that overexpression of CD98 may contribute to cell growth and survival by regulating integrin signalling, and therefore may play an important role in tumorigenesis.
PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.