Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Mouse Monoclonal (IgG1) to Human CD86
Human (tested or 100% immunogen sequence identity)
Protein A purified
Specificity and Use
CD86 antibody was raised against human peripheral blood lymphocytes.
Recognizes the human CD86 antigen, a cell surface protein expressed by activated B cells and monocytes. CD86 is also known as B7-2 and is the second ligand for CD28 and CTLA-4 and may have an important role in co-stimulation of T cells in the primary immune response.
Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Lyophilized from PBS, pH 7.2, 0.1% sodium azide, 1% BSA.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. It is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell.