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Anti-CD86 Antibody LS-C44890

Note: This antibody replaces LS-C57980, LS-C44887

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $235
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD86 Antibodies

Anti-CD86 Antibody (clone BU63, FITC) LS-C112510
Mouse Monoclonal [clone BU63] (IgG1) to Human CD86
Human
Flow Cytometry
FITC Conjugated
Anti-CD86 Antibody IHC-plus™ LS-B11911
Rabbit Polyclonal (IgG) to Human CD86
Human, Mouse
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal (IgG2b) to Mouse CD86
Mouse
Flow Cytometry (applications tested for the base form of this product only)
Unconjugated

Details

Mouse CD86
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Unconjugated. Also available conjugated with FITC, FITC, RPE.
Protein G purified
Unmodified

Applications

  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

CD86 antibody was raised against mouse B-cell line, BCL1.
Recognizes mouse CD86 (B7-2), an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse CD86 is expressed at high levels on peripheral blood monocytes and dendritic cells, and at low levels on resting B and T-lymphocytes. Expression of CD86, on these cell populations, can be increased upon activation. CD86 has been identified, along with CD80 (B7-1), as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses. The PO3 antibody has been reported to block some co-stimulatory functions of CD86. XXX recommend the use of MCA2463EL for this purpose.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About CD86

P42081 NM_006889 NP_008820.3

CD86 Antibody, Activation B7-2 antigen Antibody, B7-2 Antibody, B7.2 Antibody, B70 Antibody, CD86 molecule Antibody, CTLA-4 counter-receptor B7.2 Antibody, CD86 antigen Antibody, FUN-1 Antibody, LAB72 Antibody, BU63 Antibody, CD28LG2 Antibody, Ctla-4 counter-receptors b7.2 Antibody

CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. It is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell.

Requested From: United States
Date Requested: 12/10/2016

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