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Anti-CD86 Antibody (FITC) LS-C44889

Note: This antibody replaces LS-C57978

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $285
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD86 Antibodies

Anti-CD86 Antibody (clone BU63, FITC) LS-C112510
Mouse Monoclonal [clone BU63] (IgG1) to Human CD86
Human
Flow Cytometry
FITC Conjugated
Anti-CD86 Antibody IHC-plus™ LS-B11911
Rabbit Polyclonal (IgG) to Human CD86
Human, Mouse
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal (IgG2b) to Mouse CD86
Mouse
Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated

Details

Mouse CD86
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Fluorescein. Also available Unconjugated or conjugated with FITC, RPE.
Protein G purified
Unmodified

Applications

  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

CD86 antibody was raised against mouse B-cell line, BCL1.
Recognizes mouse CD86 (B7-2), an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse CD86 is expressed at high levels on peripheral blood monocytes and dendritic cells, and at low levels on resting B and T-lymphocytes. Expression of CD86, on these cell populations, can be increased upon activation. CD86 has been identified, along with CD80 (B7-1), as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses. The PO3 antibody has been reported to block some co-stimulatory functions of CD86. XXX recommend the use of MCA2463EL for this purpose.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
For research use only.

About CD86

P42081 NM_006889 NP_008820.3

CD86 Antibody, Activation B7-2 antigen Antibody, B7-2 Antibody, B7.2 Antibody, B70 Antibody, CD86 molecule Antibody, CTLA-4 counter-receptor B7.2 Antibody, CD86 antigen Antibody, FUN-1 Antibody, LAB72 Antibody, BU63 Antibody, CD28LG2 Antibody, Ctla-4 counter-receptors b7.2 Antibody

CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. It is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell.

Requested From: United States
Date Requested: 12/5/2016

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