(tested or 100% immunogen sequence identity)
Also available conjugated with FITC
, Cy5, RPE
Protein A purified
- IHC - Frozen (1:20 - 1:100)
- Flow Cytometry (1:20 - 1:100)
- (applications tested for the base form of this product only)
See our complete line of Immunohistochemistry Reagents
including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
CD86 antibody was raised against human peripheral blood lymphocytes.
Recognizes human CD86 also known as B7-2, a type I transmembrane protein expressed by monocytes and activated B cells. CD86 acts as a co-stimulatory molecule along with CD80 and is a ligand for CD28 and CTLA-4. CD86 is a member of the Immunoglobulin superfamily and carries an extracellular domain bearing both an domain which contains the CTLA-4 binding site and an adjacent C2-like domain. CD86 plays an important role in co-stimulation of T cell proliferation, IL-2 production and in the primary immune response. Domain depletion epitope mapping studies indicate that the binding site of Mouse anti Human CD86, is located within the Ig-v-like domain of human CD86. Studies suggest that CD86 along with CD80 may be exploited as receptors for adenovirus entry into cells.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
PBS, 0.09% sodium azide
4°C or -20°C, Avoid freeze-thaw cycles.
For research use only.
This antibody carries the LSBio 100% Guarantee.