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| Catalog Number | Size | Price |
|---|---|---|
| LS-C188425-100 | 100 Tests | $502 |
Monoclonal Mouse anti‑Rat CD86 Antibody (clone 24F, RPE) LS‑C188425
Monoclonal Mouse anti‑Rat CD86 Antibody (clone 24F, RPE) LS‑C188425
Antibody:
CD86 Mouse anti-Rat Monoclonal (RPE) (24F) Antibody
Application:
Flo
Reactivity:
Rat
Format:
R. Phycoerythrin, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CD86 Mouse anti-Rat Monoclonal (RPE) (24F) Antibody
Application:
Flo
Reactivity:
Rat
Format:
R. Phycoerythrin, Unmodified
Specifications
Description
CD86 antibody LS-C188425 is an RPE-conjugated mouse monoclonal antibody to rat CD86. Validated for Flow.
Target
Rat CD86
Synonyms
CD86 | Activation B7-2 antigen | B7-2 | B7.2 | B70 | CD86 molecule | CTLA-4 counter-receptor B7.2 | CD86 antigen | FUN-1 | LAB72 | BU63 | CD28LG2 | Ctla-4 counter-receptors b7.2
Host
Mouse
Reactivity
Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
24F
Conjugations
R. Phycoerythrin
Purification
Protein G purified
Modifications
Unmodified
Immunogen
HTLV-1 transformed Lewis - S1 cells.
Specificity
Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86.
Applications
- Flow Cytometry (1:1)
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with distilled water.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CD86
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Species:
Human
Applications:
IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/25/2024
Date Requested: 4/25/2024
