Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-C188422-0.5 0.5 mg $626 
CD86 Antibody - Flow cytometry of rat splenocytes with Mouse anti-Rat CD86:Low Endotoxin This image was taken for the unmodified form of this product. Other forms have not been tested.

Monoclonal Mouse anti‑Rat CD86 Antibody (clone 24F, Low Endotoxin, IHC) LS‑C188422

Monoclonal Mouse anti‑Rat CD86 Antibody (clone 24F, Low Endotoxin, IHC) LS‑C188422

Antibody:
CD86 Mouse anti-Rat Monoclonal (Low Endotoxin) (24F) Antibody
Application:
IHC-Fr, IP, Flo
Reactivity:
Rat
Format:
Unconjugated, Low Endotoxin
Price
Catalog Number
$626
LS-C188422-0.5
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
CD86 Mouse anti-Rat Monoclonal (Low Endotoxin) (24F) Antibody
Application:
IHC-Fr, IP, Flo
Reactivity:
Rat
Format:
Unconjugated, Low Endotoxin

Specifications

Description
CD86 antibody LS-C188422 is an unconjugated mouse monoclonal antibody to rat CD86. Validated for Flow, IHC and IP.
Target
Rat CD86
Synonyms
CD86 | Activation B7-2 antigen | B7-2 | B7.2 | B70 | CD86 molecule | CTLA-4 counter-receptor B7.2 | CD86 antigen | FUN-1 | LAB72 | BU63 | CD28LG2 | Ctla-4 counter-receptors b7.2
Host
Mouse
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
24F
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Low Endotoxin
Immunogen
HTLV-1 transformed Lewis - S1 cells.
Specificity
Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86.
Applications
  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:25 - 1:200)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Presentation
PBS
Storage
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD86
P42081 NM_006889 NP_008820.3

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/25/2024