Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Mouse Monoclonal (IgG1) to Human CD86
IHC, Western blot, Flow Cytometry
Human (tested or 100% immunogen sequence identity)
Protein A purified
Specificity and Use
CD86 antibody was raised against aRH-77 (B-lymphoblastoid cell line).
Recognizes the CD86 molecule of 80kD.
Antibody blocks MLR and blocks binding of soluble CD152-muIg fusion protein to CD. Applications: Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
FBS, 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5% glycerol, 0.2% BSA, 0.04% sodium azide.
CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. It is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell.