Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein A purified
IHC - Frozen
Flow Cytometry (1:50)
Specificity and Use
CD83 antibody was raised against cOS cells transfected with human CD83.
Recognizes the human CD83 molecule of 45kD.
Suitable for use in Flow Cytometry and Immunohistochemistry (frozen). Flow Cytometry: 1:50 (80 ul/test). The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
CD83 is a member of the Ig superfamily. It contains an extracellular V-type domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 is used as a marker for mature, antigen presenting dendritic cells that are capable of generating tumor specific T cell immunity. CD83 is expressed by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centers.