Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CD83 is a member of the Ig superfamily. It contains an extracellular V-type domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 is used as a marker for mature, antigen presenting dendritic cells that are capable of generating tumor specific T cell immunity. CD83 is expressed by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centers.