Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone C33] (IgG2a) to Human CD82
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [C33]
Protein A purified
Specificity and Use
CD82 antibody was raised against c91/PL (human HTLV-1+ T cell line).
Monoclonal antibody C33 reacts with CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
The reagent is designed for Flow Cytometry analysis of human blood cells using 4 ul reagent / 100 ul of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.2% BSA, 0.02% sodium azide.
Store in the dark at 2-8 C. Do not freeze. Avoid prolonged exposure to light.
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients.