Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey, Horse (tested or 100% immunogen sequence identity)
Bat, Bovine, Dog, Hamster (at least 90% immunogen sequence identity)
Protein G purified
Specificity and Use
CD82 antibody was raised against synthetic peptide from human CD82. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Horse (100%); Hamster, Bovine, Bat, Dog, Opossum (93%); Mouse, Rat, Pig, Platypus (87%).
KLH conjugated synthetic peptide comprising amino acids 253 - 267 [CRHVHSEDYSKVPKY] of the human kangai 1 (KAI1, CD82) protein.
PBS, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients.