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Anti-CD81 Antibody LS-C43994

Note: This antibody replaces LS-C57510, LS-C43991

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $235
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD81 Antibodies

Anti-CD81 Antibody (clone 1.3.3.22, Biotin) LS-C35761
Mouse Monoclonal [clone 1.3.3.22] (IgG1) to Human CD81
Human
Western blot, Flow Cytometry
Biotin Conjugated
Anti-CD81 Antibody (clone 1.3.3.22, Biotin) LS-C134650
Mouse Monoclonal [clone 1.3.3.22] (IgG1) to Human CD81
Human
Western blot, Flow Cytometry
Biotin Conjugated
Flow Cytometry Image
Anti-CD81 Antibody (clone 1.3.3.22) IHC-plus™ LS-B7347
Mouse Monoclonal [clone 1.3.3.22] (IgG1) to Human CD81
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Hamster Monoclonal (IgG1) to Mouse CD81
Mouse, Rat
Western blot, Immunoprecipitation, Flow Cytometry, ELISA (applications tested for the base form of this product only)
Unconjugated

Details

Mouse CD81
Hamster
Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Unconjugated. Also available conjugated with Biotin, FITC, RPE.
Protein G purified
Unmodified

Applications

  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:10 - 1:50)
  • ELISA
  • (applications tested for the base form of this product only)

Specificity and Use

CD81 antibody was raised against 38C13, murine B cell line.
Recognizes mouse and rat CD81, also known as TAPA-1 or Target of the antiproliferative antibody 1. CD81 is a 236 amino acid ~26 kD multipass transmembrane protein belonging to the TM4SF family. In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation. Induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation. Eat 2 requires the presence of both extracellular loops of TAPA-1 for binding. Mice lacking CD81 demonstrate reduced fertility through impaired oocyte-sperm fusion, double knockout CD81-/- CD9-/- mice are completely infertile suggesting complementary roles in oocyte-sperm fusion.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CD81

P60033 NM_004356 NP_004347.1

CD81 Antibody, CD81 antigen Antibody, CD81 molecule Antibody, CVID6 Antibody, S5.7 Antibody, TAPA1 Antibody, TAPA-1 Antibody, Tetraspanin-28 Antibody, TSPAN28 Antibody, Tspan-28 Antibody

CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins.

Requested From: United States
Date Requested: 2/21/2017

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