Mouse CD80

Rat

Mouse (tested or 100% immunogen sequence identity)

IgG2a Monoclonal

RMMP-1

Phycoerythrin

Purified

Unmodified

Reacts with the murine CD80 (B7-1) molecule. This member of the Ig superfamily, along with CD86 (B7-2), participates in T cell costimulation via interactions with CD28 and CTLA-4. CD80 is constitutively expressed on dendritic cells, monocytes, and peritoneal macrophages; and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours. Applications include: flow cytometry.

• Flow Cytometry (1 µg/10E6 cells)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS, 0.9% Sodium Azide, 1% BSA

Store at 4°C. Do not freeze. Protect from light. Store undiluted.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P33681 NCBI: NM_005191 NP_005182.1