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| Catalog Number | Size | Price |
|---|---|---|
| LS-C188088-100 | 100 Tests | $732 |
1 of 2
2 of 2
Monoclonal Rat anti‑Dog CD8 Antibody (clone YCATE55.9, RPE) LS‑C188088
Monoclonal Rat anti‑Dog CD8 Antibody (clone YCATE55.9, RPE) LS‑C188088
Antibody:
CD8 Rat anti-Dog Monoclonal (RPE) (YCATE55.9) Antibody
Application:
Flo
Reactivity:
Dog
Format:
R. Phycoerythrin, Unmodified
Other formats:
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CD8 Rat anti-Dog Monoclonal (RPE) (YCATE55.9) Antibody
Application:
Flo
Reactivity:
Dog
Format:
R. Phycoerythrin, Unmodified
Other formats:
Specifications
Description
CD8 antibody LS-C188088 is an RPE-conjugated rat monoclonal antibody to dog CD8. Validated for Flow. Cited in 1 publication.
Host
Rat
Reactivity
Dog
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
YCATE55.9
Conjugations
R. Phycoerythrin.
Also available Unconjugated or conjugated with FITC.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Canine CD8 alpha chimeric human IgG1 Fc fusion protein.
Specificity
Was clustered as Canine CD8 in the First Canine Leukocyte Antigen Workshop. YCATE55.9 reacts with a rat cell line transfected with cDNA for canine CD8alpha and blocks MHC class I dependant T-cell responses in vitro and in vivo. Has been shown to deplete circulating CD8+ T cells when administered to dogs in vivo. Reduced levels of circulating CD8+ T cells has been associated with decreased survival times for dogs with osteosarcoma.
Applications
- Flow Cytometry (1:1)
- Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with distilled water.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
LSBio Ratings
CD8 Antibody (clone YCATE55.9, RPE) for Flow LS-C188088 has an LSBio Rating of
Publications (4)
Learn more about The LSBio Ratings Algorithm
Publications (1)
A canine chimeric monoclonal antibody targeting PD-L1 and its clinical efficacy in canine oral malignant melanoma or undifferentiated sarcoma. Maekawa N, Konnai S, Takagi S, Kagawa Y, Okagawa T, Nishimori A, Ikebuchi R, Izumi Y, Deguchi T, Nakajima C, Kato Y, Yamamoto K, Uemura H, Suzuki Y, Murata S, Ohashi K. Scientific reports. 2017 7:8951. (Flo; Dog)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC - Paraffin, IHC - Frozen
Species:
Rat
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Species:
Mouse
Applications:
IHC, IHC - Frozen, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
