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Anti-CD8 Antibody (clone YCATE55.9) LS-C187454


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $390
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-C188087 FITC Conjugated
LS-C188088 RPE Conjugated

Most Popular CD8 Antibodies

Anti-CD8 Antibody (clone 12.C7, FITC) LS-C43770
Mouse Monoclonal [clone 12.C7] (IgG1) to Rabbit CD8
Flow Cytometry
FITC Conjugated
Anti-CD8 Antibody (C-Terminus, clone SP239) LS-C210453
Rabbit Monoclonal [clone SP239] (IgG) to Human CD8
IHC - Paraffin
Immunohistochemistry Image
Anti-CD8 Antibody (clone 4B11) LS-C11593
Mouse Monoclonal [clone 4B11] (IgG2b) to Human CD8
IHC - Paraffin, IHC - Frozen, Western blot

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone YCATE55.9] (IgG1) to Dog CD8
IHC - Frozen, Immunofluorescence, Flow Cytometry (applications tested for the base form of this product only)


Dog CD8
Dog (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [YCATE55.9]
Protein G purified


  • IHC - Frozen
  • Immunofluorescence
  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

CD8 antibody was raised against canine CD8a chimeric human IgG1 Fc fusion protein.
Was clustered as Canine CD8 in the First Canine Leukocyte Antigen Workshop. YCATE55.9 reacts with a rat cell line transfected with cDNA for canine CD8alpha and blocks MHC class I dependant T-cell responses in vitro and in vivo. Has been shown to deplete circulating CD8+ T cells when administered to dogs in vivo. Reduced levels of circulating CD8+ T cells has been associated with decreased survival times for dogs with osteosarcoma.


PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CD8

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. There are two isoforms of the protein, alpha and beta, each encoded by a different gene. In humans, both genes are located on chromosome 2 in position 2p12.

Flow Cytometry

Flow Cytometry
Flow cytometry of canine peripheral blood lymphocytes with Rat anti-Dog CD8. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/24/2016

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