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CD68
CD68 molecule
CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
| Gene Name: | CD68 molecule |
| Synonyms: | CD68, CD68 antigen, gp110, SCARD1, CD68 molecule, LAMP4, Macrophage antigen CD68, Macrosialin |
| Target Sequences: | NM_001251 NP_001242.2 P34810 |
Publications (5)
1
Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression. Lyon CA, Williams H, Bianco R, Simmonds SJ, Brown BA, Wadey KS, Smith FCT, Johnson JL, George SJ. Scientific reports. 2017 December;7:17342. (Mouse)
[Full Text Article]
[PubMed:29229950]
[PMC:PMC5725451]
2
CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains. Chancellor A, Tocheva AS, Cave-Ayland C, Tezera L, White A, Al Dulayymi JR, Bridgeman JS, Tews I, Wilson S, Lissin NM, Tebruegge M,, Marshall B,, Sharpe S, Elliott T, Skylaris CK, Essex JW, Baird MS, Gadola S, Elkington P,, Mansour S. Proceedings of the National Academy of Sciences of the United States of America. 2017 December;114:E10956-E10964. [Full Text Article]
[PubMed:29158404]
[PMC:PMC5754766]
Related Antibodies: LS-C188452.
3
Reduced patency in left-sided arteriovenous grafts in a porcine model. Shirley Liu, Tun Wang, Juan Wang, Toshihiko Isaji, Shun Ono, Arash Fereydooni, Ryosuke Taniguchi, Yutaka Matsubara, Laura E Niklason, Alan Dardik. Journal of vascular surgery. 2020 July;72:305-317.e6. [Full Text Article]
[PubMed:31699515]
[PMC:PMC7196525]
Related Antibodies: LS-C187543.
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(6)
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(85)
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Publications
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(228)
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(6)
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(1)
CD68 Mouse anti-Human Monoclonal (KP1) Antibody
Human
Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
0.1 mg/$460
CD68 Mouse anti-Rat Monoclonal (ED1) Antibody
Rat
IHC, IHC-Fr, IHC-P
Unconjugated
125 µg/$485
CD68 Mouse anti-Human Monoclonal (KP1) Antibody
Rat, Cat, Human, Monkey
IHC, IHC-P
Unconjugated
125 µl/$565
CD68 Mouse anti-Human Monoclonal (FITC) (KP1) Antibody
Human
Flo, IF
FITC Conjugated
0.1 mg/$432
Cancer Pathology
Cancer
CD68 Rabbit anti-Human Recombinant Monoclonal (C68/2908R) Antibody
Human
IHC-P, WB
Unconjugated
100 µg/$525
CD68 Rat anti-Mouse Monoclonal (FA-11) Antibody
Mouse
Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
25 µg/$301; 0.1 mg/$435; 0.25 mg/$545
CD68 Rat anti-Mouse Monoclonal (FITC) (FA-11) Antibody
Mouse
Flo, IHC, IHC-Fr, IHC-P
FITC Conjugated
50 µg/$320; 0.1 mg/$474
CD68 Rabbit anti-Mouse Polyclonal (aa312-326) Antibody
Mouse, Rat
IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CD68 Rabbit anti-Human Polyclonal (aa341-354) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CD68 Rabbit anti-Human Polyclonal (aa209-237) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
CD68 Rat anti-Mouse Monoclonal (FITC) Antibody
Mouse
Flo
FITC Conjugated
50 µg/$508; 100 µg/$807
CD68 Mouse anti-Rat Monoclonal (PE) Antibody
Bovine, Rat
Flo
PE Conjugated
100 Tests/$913
CD68 Mouse anti-Human Monoclonal (C68/684) Antibody
Mouse, Rat, Cat, Human, Monkey
Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
CD68 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (C68/684) Antibody
Mouse, Rat, Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
50 µg/$460
CD68 Rat anti-Mouse Monoclonal Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$634; 250 µg/$901
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD68 Mouse anti-Human Monoclonal (aa22-319) (OTI8A4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
CD68 Mouse anti-Rat Monoclonal (ED1) Antibody
Rat
Flo, IF, IHC, IHC-Fr, IHC-P, IP, RIA, WB
Unconjugated
250 µg/$547
CD68 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$432
CD68 Rat anti-Mouse Monoclonal (Low Endotoxin) (FA-11) Antibody
Mouse
Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Low Endotoxin
0.5 mg/$671
CD68 Mouse anti-Human Monoclonal (SPM130) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
CD68 Mouse anti-Rat Monoclonal (FITC) Antibody
Rat
Flo
FITC Conjugated
100 µg/$913
CD68 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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product results
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