Human CD66acd

Rat

Human (tested or 100% immunogen sequence identity)

IgG2a Monoclonal

YTH71.3

Unconjugated

Affinity purified

Unmodified

Human lymphocytes.

Recognizes 3 members of the human CD66 family, namely CD66a, also known as Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1 or CEACAM1. Clone YTH71.3 also recognizes CD66c, known as Carcinoembryonic antigen-related cell adhesion molecule 6 or Non-specific cross-reacting antigen. In addition the clone also recognizes CD66d which in turn is also known as Carcinoembryonic antigen-related cell adhesion molecule 3 or CGM1. CD66 family members are single pass, type 1 membrane glycoproteins bearing a single domain and a varying number of domains. Clone YTH71.3 recognizes epitopes in the of these CD66 family members. CD66 members are expressed by human neutrophils and cells of the colon where it is down regulated in some cases of colon carcinoma. CD66a is also expressed in the human alveolar adenocarcinoma cell line A549 and may play a role in Moraxella catarrhalis induced apoptosis of pulmonary epithelial cells in diseases including COPD and emphysema.

• IHC
• IHC - Paraffin (10 µg/ml)
• IHC - Frozen
• Flow Cytometry

Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells in 100 ul. Method sheets are available on request.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.