Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone YTH71.3] (IgG2a) to Human CD66acd
Human, Rhesus monkey
IHC - Frozen, Flow Cytometry
Human, Rhesus monkey (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [YTH71.3]
IHC - Frozen
Specificity and Use
CD66acd antibody was raised against human lymphocytes.
Recognizes 3 members of the human CD66 family, namely CD66a, also known as Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1 or CEACAM1. Clone YTH71.3 also recognizes CD66c, known as Carcinoembryonic antigen-related cell adhesion molecule 6 or Non-specific cross-reacting antigen. In addition the clone also recognizes CD66d which in turn is also known as Carcinoembryonic antigen-related cell adhesion molecule 3 or CGM1. CD66 family members are single pass, type 1 membrane glycoproteins bearing a single domain and a varying number of domains. Clone YTH71.3 recognizes epitopes in the of these CD66 family members. CD66 members are expressed by human neutrophils and cells of the colon where it is down regulated in some cases of colon carcinoma. CD66a is also expressed in the human alveolar adenocarcinoma cell line A549 and may play a role in Moraxella catarrhalis induced apoptosis of pulmonary epithelial cells in diseases including COPD and emphysema.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells in 100 ul. Method sheets are available on request.
0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.