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Anti-CD65s Antibody (clone VIM-2) LS-C188329

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $250
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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Mouse Monoclonal [clone VIM-2] (IgM) to Human CD65s
Human
IHC - Frozen, Immunofluorescence, Flow Cytometry (applications tested for the base form of this product only)
Unconjugated

Details

Human CD65s
Mouse
Human (tested or 100% immunogen sequence identity)
IgM Monoclonal [VIM-2]
Unconjugated. Also available conjugated with FITC.
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Frozen (1:20)
  • Immunofluorescence
  • Flow Cytometry (1:20 - 1:200)
  • (applications tested for the base form of this product only)

Specificity and Use

CD65s antibody was raised against tHP1 (human acute monocytic leukaemia cells).
Selectively recognizes the sialylated form of human CD65, known as CD65s (VIM-2 antigen), a leucocyte carbohydrate antigen expressed by granulocytes, monocytes and leukemic cells of myelomonocytic lineage. CD65s is aberrantly expressed on some acute myeloid leukemias (AML) and clone VIM-2 has been reliably used as a marker for distinguishing between mature and undifferentiated AML. During normal myelopoiesis, expression of CD65s follows the disappearance of the progenitor antigen CD34. Cross-linking of the CD65s antigen using clone VIM-2, has been shown to induce phagocyte cytoplasmic calcium flux, oxidative burst and degranulation.

Packaging

PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CD65s


Requested From: United States
Date Requested: 12/10/2016

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