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Anti-CD63 Antibody (clone AD1, FITC) LS-C188588

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $370
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD63 Antibodies

Anti-CD63 Antibody (clone AHN16.1/46-4-5, Biotin) LS-C35717
Mouse Monoclonal [clone AHN16.1/46-4-5] (IgG1) to Human CD63
Human
Flow Cytometry
Biotin Conjugated
Anti-CD63 Antibody LS-C204227
Goat Polyclonal (IgG) to Human CD63
Human, Monkey, Mouse, Rat, Dog
Immunofluorescence, Western blot
Unconjugated
Immunofluorescence Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone AD1] (IgG1) to Rat CD63
Rat
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated

Details

Rat CD63
Mouse
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [AD1]
Fluorescein. Also available Unconjugated.
Protein G purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1)
  • (applications tested for the base form of this product only)

Specificity and Use

CD63 antibody was raised against rBL-2H3 rat basophilic leukaemia cell line.
Recognizes rat CD63, an intracellular type-III lysosomal glycoprotein and member of the tetraspanin (TM4SF) family, which is translocated to the cell surface upon activation of platelets, and therefore a potential indicator of platelet activation. Rat CD63 is expressed on mast cells, and studies using clone AD1, have shown that it is located near to FcER1, and that clone AD1 partially inhibits IgE-mediated histamine release.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide, 1% BSA
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
For research use only.

About CD63

P08962 NM_001780 NP_001771.1

CD63 Antibody, CD63 molecule Antibody, LAMP-3 Antibody, ME491 Antibody, Granulophysin Antibody, MLA1 Antibody, Tetraspanin-30 Antibody, Tspan-30 Antibody, CD63 antigen Antibody, OMA81H Antibody, TSPAN30 Antibody

Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2.

Flow Cytometry

Flow Cytometry
Rat peripheral blood platelets stained with Mouse anti-Rat CD63:FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/6/2016

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