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Anti-CD60 Antibody LS-C43458


Wt. Vol. Conc. Price
- 2000 µl - Unavailable

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100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgM) to Human CD60
Human, Fish
IHC - Frozen, Immunoprecipitation, Flow Cytometry


Human CD60
Human, Fish (tested or 100% immunogen sequence identity)
IgM Monoclonal
Gel filtration


  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:1)

Specificity and Use

CD60 antibody was raised against purified CD60 antigen from PBL; 9-0-acetyl-GD3 from buttermilk.
Recognizes the human CD60 antigen, a carbohydrate structure GD3 (Neu5Aca8Neu5Aca3Galbeta4GlcCer) modified by a terminal 9-0-acetylated disialosyl group (9-O-acetyl GD3). Does not recognize 7-O-acetyl GD3 or non-acetylated GD3. CD60 has been divided into 3 sub-types depending on the acetylation present. Non acetylated GD3 is termed CD60a and 7-O-acetyl GD3 termed CD60c. 9-O-acetyl GD3 as recognized by clone M-T6004 has been designated CD60b. CD60b is present on CD8+ve helper T cells, CD4+ve memory T cells and on activated B cells. Expression has also been reported on neuroectodermal cells and in breast carcinomas. CD60b is not expressed by naive T cells. GD3 has been described as a pro-apoptotic messenger targeting mitochondria in many lymphoid and myeloid cell types. Acetylation abrogates the pro-apoptotic activity of GD3 and CD60b protects tumor cells from apoptosis.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.


PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
For research use only.

About CD60

Requested From: 
Date Requested: 3/28/2017

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