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Anti-CD46 Antibody (clone MEM-258) LS-C204148


Wt. Vol. Conc. Price
100 µg - - $295
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CD46 Antibodies

Anti-CD46 Antibody (clone 13/42) LS-C96281
Mouse Monoclonal [clone 13/42] (IgG1)
IHC - Paraffin, IHC - Frozen
Immunohistochemistry Image
Anti-CD46 Antibody (clone MEM-258) IHC-plus™ LS-B5950
Mouse Monoclonal [clone MEM-258] (IgG1) to Human CD46
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone MEM-258] (IgG1) to Human CD46
Western blot, Immunoprecipitation, Flow Cytometry


Human CD46
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MEM-258]


  • Western blot
  • Immunoprecipitation
  • Flow Cytometry

Specificity and Use

CD46 antibody was raised against hPB-ALL cells.
CD46 antigen (human). The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome.


PBS, pH 7.4, 15 mM sodium azide
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CD46

P15529 NM_002389 NP_002380.3

CD46 Antibody, AHUS2 Antibody, CD46 antigen Antibody, MCP Antibody, Measles virus receptor Antibody, TLX Antibody, MIC10 Antibody, TRA2.10 Antibody, Membrane cofactor protein Antibody

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells.

Requested From: United States
Date Requested: 10/24/2016

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