Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CD45.2 antibody was raised against pVG RT7.2 +ve rat thymocytes.
Recognizes the rat RT7.2 alloantigen - it does not react with RT7.1. RT7.2 is expressed on the surface of all peripheral leucocytes, as well as on bone marrow cells of lymphoid and myeloid lineage. Immunoprecipitation studies demonstrate a band of 180kD from thymocytes, and 190-220kD from T and B cells. Sequential immunoprecipitation studies have revealed Recognizes a determinant of the leucocyte common antigen (LCA, CD45).
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.