Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone K252-1E4] (IgG1) to Pig CD45 / LCA
Pig CD45 / LCA
Pig (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [K252-1E4]
Protein G purified
Flow Cytometry (1:1)
Specificity and Use
CD45 / LCA antibody was raised against porcine Peripheral Blood lymphocytes.
Recognizes an epitope common to all porcine CD45 isoforms. CD45 is also known as leukocyte common antigen (LCA). Immunoprecipitates three polypeptides of 226, 210 and 190 kD from preparations of porcine peripheral blood mononuclear cells and shows a broad reactivity pattern with both lymphoid and myeloid cells.
PBS, 0.09% sodium azide, 1% BSA
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP.