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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD44 Antibody (clone BU75) LS‑C134722
CD44 antibody LS-C134722 is an unconjugated mouse monoclonal antibody to human CD44. Validated for Flow, Func and WB.
Catalog
Size
Price
LS-C134722-100
100 µg
Unavailable

Popular CD44 Products

Antibody
Species: Human, Mouse, Rat, Bovine, Dog, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, ELISA, Radioimmunoassay
Anti-CD44 antibody IHC of human uterus, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1862 concentration 10 ug/ml.
Species: Human, Dog, Pig
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry, Inhibition
Antibody
Species: Human
Applications: Immunofluorescence, Flow Cytometry, Blocking
Antibody
Species: Human
Applications: Immunofluorescence, Flow Cytometry, Blocking
Anti-CD44 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6050 dilution 1:50.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA

Product Description

CD44 antibody LS-C134722 is an unconjugated mouse monoclonal antibody to human CD44. Validated for Flow, Func and WB.
About CD44
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. P16070 NM_000610 NP_000601.3

CD44 Antibody, CDW44 Antibody, CD44 antigen Antibody, Cell surface glycoprotein CD44 Antibody, CSPG8 Antibody, ECMR-III Antibody, Epican Antibody, HUTCH-I Antibody, LHR Antibody, MDU2 Antibody, MC56 Antibody, MIC4 Antibody, Hermes antigen Antibody, Hyaluronate receptor Antibody, Phagocytic glycoprotein 1 Antibody, PGP-1 Antibody, PGP-I Antibody, Pgp1 Antibody, Phagocytic glycoprotein I Antibody, MDU3 Antibody, CD44R Antibody, HCELL Antibody, Heparan sulfate proteoglycan Antibody


Specifications

Target
Human CD44
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal [BU75]
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, RPE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot
  • Flow Cytometry
  • Functional Assay
  • (applications tested for the base form of this product only)
Immunogen
CD44 antibody was raised against human peripheral myeloma cells.
Specificity
Epitope 2 of the CD44 molecule which interacts with hyaluronate (HA)mediating binding of lymphocytes to high endothelial venules.
Usage
Function: Blocks binding of HA to CD44.
Presentation
50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/ml Gentamicin sulfate
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Flow Cytometry

Flow cytometry of CD44 antibody
Flow cytometry of CD44 antibody

Flow Cytometry

Flow cytometry of CD44 antibody
Flow cytometry of CD44 antibody

Flow Cytometry

Flow cytometry of CD44 antibody
Flow cytometry of CD44 antibody

Flow Cytometry

Flow cytometry of CD44 antibody
Flow cytometry of CD44 antibody


Requested From: 
Date Requested: 6/23/2018

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