Human CD40

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

3B2

Unconjugated

Affinity purified

Unmodified

CD40-Fc.

Recognizes human CD40, a type I transmembrane glycoprotein receptor and member of the TNF-receptor superfamily, primarily expressed by B cells and professional antigen-presenting cells (APCs), which plays a vital role in T cell-B cell interactions and in germinal centre B cell selection. CD40 is a co-stimulatory molecule which mediates its immunoregulatory effects through interaction with its ligand CD154 (CD40L, gp39), playing a role in B cell proliferation and memory development, Ig class switching, activation of APCs and subsequent cytokine production, and the expansion of antigen-specific CD4+ T cells.

• IHC - Frozen (10 µg/ml)
• Western blot (10 µg/ml)
• ELISA (1 µg/ml)

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P25942 NCBI: NM_001250 NP_001241.1