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CD33
CD33 molecule
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
| Gene Name: | CD33 molecule |
| Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
| Synonyms: | CD33, CD33 antigen, CD33 molecule, gp67, SIGLEC-3, p67, CD33 antigen (gp67), SIGLEC3 |
| Target Sequences: | NM_001772 NP_001763.3 P20138 |
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CD33
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Reactivity
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(147)
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(14)
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(4)
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(4)
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(3)
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(8)
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(4)
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(2)
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(7)
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Low endotoxin level
(8)
Cancer Pathology
Cancer
CD33 Mouse anti-Human Monoclonal (aa42-159) (44M12D3) Antibody
Human
IHC-P, WB
Unconjugated
0.1 mg/$460
Cancer Pathology
Cancer
CD33 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
CD33 Mouse anti-Human Monoclonal (aa15-237) (2C6B7) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$459
CD33 Mouse anti-Human Monoclonal (Low Endotoxin) (WM53) Antibody
Human, Non-Human Primates
Flo, Func, ICC, IHC, IHC-Fr, IP, WB
Unconjugated, Low Endotoxin
0.1 mg/$302
CD33 Mouse anti-Human Monoclonal (CD33 1C7/1) Antibody
Human
ELISA, Flo, IP, WB
Unconjugated
200 µg/$480
CD33 Mouse anti-Human Monoclonal (OTI2C1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
CD33 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C1) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CD33 Rabbit anti-Human Polyclonal (aa12-39) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
CD33 Mouse anti-Human Monoclonal (aa337-364) (574CT16.4.4) Antibody
Human
IF, WB
Unconjugated
400 µl/$393
CD33 Mouse Monoclonal (906 (MY9)) Antibody
Human
IHC, IHC-Fr
Unconjugated
200 µg/$830
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$782
CD33 Mouse anti-Human Monoclonal (OTI1E10) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
CD33 Mouse anti-Human Monoclonal (aa15-237) (2C6B7) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$459
CD33 Mouse anti-Human Monoclonal (Azide-free, Low Endotoxin) (WM53) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Azide-free, Low Endotoxin
0.5 mg/$515
CD33 Mouse anti-Human Monoclonal (WM53) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$277
HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CD33 comprises 253 amino acids and has a predicted molecular mass of 28.2 kDa. The apparent molecular mass of the protein is approximately 40-46 kDa in SDS-PAGE under reducing conditions.
100 µg/$441; 1 mg/$1,991
CD33 Rabbit anti-Mouse Polyclonal Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
100 µg/$575
CD33 Rabbit anti-Human Polyclonal (aa12-39) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
CD33 Mouse anti-Human Monoclonal (2B7C12) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$467
CD33 Mouse anti-Human Monoclonal (WM53) Antibody
Human, Non-Human Primates
Flo, Func, ICC, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$302
CD33 Mouse anti-Human Monoclonal (WM53) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$385
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
E. coli
His-T7
28.2 kDa
50 µg/$402; 10 µg/$275; 200 µg/$802; 100 µg/$642; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
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