Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone OKT3] (IgG2a) to Human CD3
HRP Conjugated, Azide-free
Mouse Monoclonal [clone HIT3a] (IgG2a) to Human CD3
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [HIT3a]
IHC - Frozen
IHC - Paraffin
Specificity and Use
PBS buffer, pH 7.2 with 0.09% Sodium Azide
+4°C, avoid freezing
For research use only.
The CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3gamma chain, a CD3delta chain, and two CD3epsilon chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the zeta-chain to generate an activation signal in T lymphocytes. The TCR, zeta-chain, and CD3 molecules together comprise the TCR complex.