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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD27L / CD70 Antibody (clone BU69, Biotin) LS‑C134545
Note: This antibody replaces LS-C35734
CD70 antibody LS-C134545 is a biotin-conjugated mouse monoclonal antibody to human CD70 (CD27L). Validated for ELISA, Flow, Func, ICC and IHC.
Catalog
Size
Price
LS-C134545-100
100 µg (1 mg/ml)
Unavailable

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Flow cytometry of CD70 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: IHC, IHC - Frozen, ICC, Flow Cytometry, ELISA, Functional Assay

Product Description

CD70 antibody LS-C134545 is a biotin-conjugated mouse monoclonal antibody to human CD70 (CD27L). Validated for ELISA, Flow, Func, ICC and IHC.
About CD27L / CD70
CD27L / CD70 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. P32970 NM_001252 NP_001243.1

CD70 Antibody, CD27LG Antibody, Ki-24 antigen Antibody, Surface antigen CD70 Antibody, CD27 ligand Antibody, CD27-L Antibody, CD70 antigen Antibody, CD70 molecule Antibody, TNFSF7 Antibody


Specifications

Target
Human CD27L / CD70
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [BU69]
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, RPE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • ICC
  • Flow Cytometry
  • ELISA
  • Functional Assay
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CD27L / CD70 antibody was raised against human WM-1 (Waldenstrpm's macroglobulinemia) cell line.
Specificity
CD70 molecule of approximately 30 kd.
Usage
Function: Blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5% Glycerol, 0.2% BSA, 0.04% sodium azide
Storage
Store at 2-8°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Flow Cytometry

Flow cytometry of CD70 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of CD70 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of CD70 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of CD70 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of CD70 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of CD70 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of CD70 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of CD70 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/18/2018

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