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Anti-CD27L / CD70 Antibody (clone BU69, Biotin) LS-C134545
Note: This antibody replaces LS-C35734Most Popular CD27L / CD70 Antibodies
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Details
| Human CD27L / CD70 | |
| Mouse | |
| Human (tested or 100% immunogen sequence identity) | |
| IgG1 Monoclonal [BU69] | |
| Biotin | |
| Protein A purified | |
| Unmodified |
Applications
- IHC - Frozen
- ICC
- Flow Cytometry
- ELISA
- Functional Assay
Specificity and Use
| CD27L / CD70 antibody was raised against human WM-1 (Waldenstrpm's macroglobulinemia) cell line. | |
| CD70 molecule of approximately 30 kd. | |
| Function: Blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
Packaging
| 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5% Glycerol, 0.2% BSA, 0.04% sodium azide | |
| Store at 2-8°C. Do not freeze. | |
| For research use only. |
About CD27L / CD70
P32970
NM_001252
NP_001243.1
CD70 Antibody, CD27LG Antibody, Ki-24 antigen Antibody, Surface antigen CD70 Antibody, CD27 ligand Antibody, CD27-L Antibody, CD70 antigen Antibody, CD70 molecule Antibody, TNFSF7 Antibody
CD27L / CD70 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
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Requested From:
Date Requested: 8/20/2017
Date Requested: 8/20/2017
