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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD274 / B7‑H1 / PD‑L1 Antibody (clone 29E.2A3) LS‑C40827
PD-L1 antibody LS-C40827 is an unconjugated mouse monoclonal antibody to human PD-L1 (CD274 / B7-H1). Validated for Flow.
Catalog
Size
Price
LS-C40827-100
100 µg (0.5 mg/ml)
Unavailable

Popular CD274 / B7-H1 / PD-L1 Products

Flow cytometry of B7-H1 / PD-L1 / CD274 antibody
Species: Human
Applications: Flow Cytometry, ELISA
Flow cytometry of B7-H1 / PD-L1 / CD274 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry, ELISA
Flow cytometry of B7-H1 / PD-L1 / CD274 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry, ELISA
Flow Cytometry Image
Species: Human
Applications: IHC, IHC - Paraffin, Flow Cytometry
Anti-B7-H1 / PD-L1 / CD274 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10562 dilution 1:100.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

PD-L1 antibody LS-C40827 is an unconjugated mouse monoclonal antibody to human PD-L1 (CD274 / B7-H1). Validated for Flow.
About CD274 / B7-H1 / PD-L1
CD274, also known as B7-H1 and PD-L1, a cell surface glycoprotein, is a member of the B7 family of co-stimulatory molecules. CD274 is expressed constitutively on macrophages and dendritic cells, and is induced on activated T-cells, B-cells, endothelial cells and epithelial cells in response to interferons. CD274 has dual functions: inhibition of activated effector T cells and co-stimulation of naïve T cells. Q9NZQ7 NM_014143 NP_054862.1

CD274 Antibody, B7-H Antibody, B7 homolog 1 Antibody, B7-H1 Antibody, B7H1 Antibody, CD274 molecule Antibody, CD274 antigen Antibody, PDCD1 ligand 1 Antibody, PDL1 Antibody, PD-L1 Antibody, PDCD1L1 Antibody, PDCD1LG1 Antibody, Programmed death ligand 1 Antibody


Specifications

Target
Human CD274 / B7-H1 / PD-L1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal [29E.2A3]
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Flow Cytometry
Failed Applications
  • IHC - Paraffin
Immunogen
Purified human CD274.
Specificity
Full length human PD-L1
Presentation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
Storage
4°C. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Flow Cytometry

Human peripheral blood lymphocytes stained with purified 29E.2A3, followed by biotinylated anti-mouse IgG and Sav-PE
Human peripheral blood lymphocytes stained with purified 29E.2A3, followed by biotinylated anti-mouse IgG and Sav-PE

Flow Cytometry

Human peripheral blood lymphocytes stained with purified 29E.2A3, followed by biotinylated anti-mouse IgG and Sav-PE
Human peripheral blood lymphocytes stained with purified 29E.2A3, followed by biotinylated anti-mouse IgG and Sav-PE

Flow Cytometry

Human peripheral blood lymphocytes stained with purified 29E.2A3, followed by biotinylated anti-mouse IgG and Sav-PE
Human peripheral blood lymphocytes stained with purified 29E.2A3, followed by biotinylated anti-mouse IgG and Sav-PE

Flow Cytometry

Human peripheral blood lymphocytes stained with purified 29E.2A3, followed by biotinylated anti-mouse IgG and Sav-PE
Human peripheral blood lymphocytes stained with purified 29E.2A3, followed by biotinylated anti-mouse IgG and Sav-PE


Requested From: 
Date Requested: 6/21/2018

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