The Immunohistochemistry Antibody Company
|Human (tested or 100% immunogen sequence identity)|
|Ion exchange chromatography|
|Precipitates a molecule of MW55kD (120kD in non-reduced conditions) designated as the CD27 antigen. This antigen is expressed on activated T lymphocytes and belongs to a family of proteins associated with the nerve growth factor receptor. CD27 is expressed by thymocytes and peripheral T cells and also by EBV transformed B cell lines. Species cross-reactivity: Cynomolgus monkey and Rhesus monkey.|
|Flow Cytometry: Neat.|
|Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|For research use only.|
CD27 Antibody, CD27 antigen Antibody, CD27 molecule Antibody, S152 Antibody, T14 Antibody, T-cell activation antigen CD27 Antibody, CD27L receptor Antibody, T cell activation antigen S152 Antibody, TNFRSF7 Antibody, Tp55 AntibodyCD27 is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor.