Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone G3] (IgG2a) to Human CD247 / CD3 Zeta
Human CD247 / CD3 Zeta
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [G3]
Specificity and Use
CD247 / CD3 Zeta antibody was raised against synthetic peptide corresponding to 113aa the cytoplasmic domain of mouse zeta TCR subunit.
Recognizes mouse zeta TCR subunit.
Suitable for use in Flow cytometry: 10 ul labels of a neat working dilution to 10^6 cells in 100ul.
PBS, 0.09% sodium azide, 1% BSA
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. Sensitive to light.
CD247 / CD3 Zeta is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.