Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse (tested or 100% immunogen sequence identity)
IHC - Paraffin (1:50)
IHC - Frozen (1:50)
Flow Cytometry (1:50)
Specificity and Use
Cd209b antibody was raised against mouse SIGN-R1.
Recognizes murine SIGN-related 1 (SIGN-R1). Does not react with macrophages in other regions of the spleen, such as CD169+ marginal metallophils and F4/80+ red pulp macrophages. MZM of the spleen are involved in the clearance of polysaccharides.
Suitable for use in Flow Cytometry, Functional Blocking Studies, and Immunohistochemistry. Flow Cytometry: 1:50. Immunohistochemistry (frozen and paraffin): 1:50. For blocking studies in vitro, dilutions have to be made according to the amounts of SIGN-R1 to. be inactivated. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Liquid with 0.02% sodium azide. Low Endotoxin.
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C