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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD209 / DC‑SIGN Antibody (PE) LS‑C128543
Antibody
DC-SIGN antibody LS-C128543 is a PE-conjugated mouse monoclonal antibody to human DC-SIGN (CD209). Validated for Flow.
Catalog
Size
Price
LS-C128543-100
100 tst
Unavailable

Popular CD209 / DC-SIGN Products

Anti-CD209 / DC-SIGN antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B479 concentration 5 ug/ml.
Species: Human
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CIRE-transfected mouse splenocytes were surface stained with 0.5 ug PE rat IgG2a isotype control (open histogram) or PE anti-mouse CIRE (5H10) (colored histogram). Splenocytes shown are gated on CD11C+ cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: Flow Cytometry
Staining of mouse CIRE/DC-SIGN-transfected CHO cells with 0.125 ug of APC Rat IgG2a isotype control (blue histogram) or 0.125 ug APC anti-mouse CIRE (LWC06) (purple histogram). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Species: Human
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Antibody
Species: Mouse
Applications: IHC

Product Description

DC-SIGN antibody LS-C128543 is a PE-conjugated mouse monoclonal antibody to human DC-SIGN (CD209). Validated for Flow.
About CD209 / DC-SIGN
Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Q9NNX6 NM_021155 NP_066978.1

CD209 Antibody, CD209 antigen Antibody, CD209 molecule Antibody, CDSIGN Antibody, CLEC4L Antibody, DC-SIGN Antibody, HIV gpl20-binding protein Antibody, DC-SIGN1 Antibody


Specifications

Target
Human CD209 / DC-SIGN
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Phycoerythrin. Also available conjugated with Biotin, FITC, Biotin, FITC.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry
  • (applications tested for the base form of this product only)
Immunogen
CD209 / DC-SIGN antibody was raised against immature myeloid monocyte-derived dendritic cells (MDDCs).
Specificity
Recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 which is also known as CD209.
Usage
Suitable for use in Flow cytometry: Neat-1:10; 10 ul labels 10^6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
Lyophilized from PBS, pH 7.4, 1% BSA, 0.09% sodium azide
Reconstitution
100 tst Sterile buffer or distilled water
Storage
May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 1 year at 4°C. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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