Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone L26] (IgG2a,k) to Human CD20
IHC - Paraffin
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [L26]
Tissue culture supernatant
IHC - Paraffin (1:25 - 1:50)
Specificity and Use
CD20 antibody was raised against bALB/C mice were injected with human tonsil B cells.
Is specific to a 33 kD polypeptide present on the majority of B cells in peripheral blood and lymphoid tissue and also with a minor component of 30 kD. No reactivity with other hematopoietic cells has been observed.
CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members.