Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone AB75] (IgG1,k) to Human CD2
IHC - Paraffin, IHC - Frozen
Mouse Monoclonal [clone UMCD2/1E7E8] (IgG2a,k) to Human CD2
Western blot, Flow Cytometry, Functional Assay
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [UMCD2/1E7E8]
Protein A purified
Specificity and Use
CD2 antibody was raised against human rheumatoid synovial T cell line (ST-1).
T11-1 epitope of the 50 kd human CD2 molecule.
Function: Useful for studying CD2 ligand-binding mechanisms involved with T cell development and activation. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride
Store at +4°C. Do not freeze. Open under aseptic conditions.
CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes.