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Anti-CD1D Antibody (clone WTH1, Biotin) LS-C188719

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $280
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD1D Antibodies

Anti-CD1D Antibody (clone 51.1) IHC-plus™ LS-B4039
Mouse Monoclonal [clone 51.1] (IgG2b) to Human CD1D
Human
IHC - Paraffin, IHC - Frozen, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-CD1D Antibody LS-C122840
Rat Monoclonal (IgG2b) to Mouse CD1D
Mouse
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-CD1D Antibody IHC-plus™ LS-B12894
Rabbit Polyclonal (IgG) to Human CD1D
Human, Mouse, Rat
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone WTH1] (IgG2a) to Rat CD1D
Rat, Mouse
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, ELISA, Functional Assay
Biotin Conjugated

Details

Rat CD1D
Mouse
Rat, Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [WTH1]
Biotin
Protein A purified
Unmodified

Applications

  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1000)
  • ELISA
  • Functional Assay

Specificity and Use

CD1D antibody was raised against rat CD1d-transduced M12.4.1. C3 cells.
Recognizes rat CD1d, a glycoprotein expressed on cortical thymocytes, certain T-cell leukemias and various other antigen presenting cells. CD1d binds self and non-self glycolipids and presents them to T-cell receptors on natural killer cells. When activated, natural killer cells produce Th1 and Th2 cytokines. Clone WTH1 recognizes a different, non-overlapping epitope than clone WTH2 (, or ), and binds with high affinity to the mature CD1d heavy chain independently of beta-2-microglobulin. Clone WTH1 efficiently blocks rat and mouse invariant natural killer T cell (iNKT cell) response to a-GalCer (an antigen for iNKT cells) and has a slightly higher affinity to native CD1d than clone WTH2. Clone WTH1 cross reacts weakly with mouse tissue in IHC and western blotting, but reacts strongly with both rat and mouse antigens in flow cytometry and immunoprecipitation.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.02% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CD1D

P15813 NM_001766 NP_001757.1

CD1D Antibody, CD1D antigen, d polypeptide Antibody, R3 Antibody, R3G1 Antibody, CD1d antigen Antibody, CD1d molecule Antibody, Thymocyte antigen CD1D Antibody

CD1D is a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1.

Requested From: United States
Date Requested: 12/5/2016

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