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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD1D Antibody (clone WTH1, Biotin) LS‑C188719
Antibody
CD1D antibody LS-C188719 is a biotin-conjugated mouse monoclonal antibody to CD1D from mouse and rat. Validated for ELISA, Flow, Func, IHC, IP and WB.
Catalog
Size
Price
LS-C188719-100
100 µg (0.5 mg/ml)
Unavailable

Popular CD1D Products

Antibody
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Immunoprecipitation
Anti-CD1D antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4039 concentration 20 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Flow Cytometry
Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Western blot of CD1D (arrow) using rabbit polyclonal CD1D Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD1D gene.
Species: Human
Applications: Western blot
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot

Product Description

CD1D antibody LS-C188719 is a biotin-conjugated mouse monoclonal antibody to CD1D from mouse and rat. Validated for ELISA, Flow, Func, IHC, IP and WB.
About CD1D
CD1D is a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. P15813 NM_001766 NP_001757.1

CD1D Antibody, CD1D antigen, d polypeptide Antibody, R3 Antibody, R3G1 Antibody, CD1d antigen Antibody, CD1d molecule Antibody, Thymocyte antigen CD1D Antibody


Specifications

Target
Rat CD1D
Host
Mouse
Reactivity
Rat, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal [WTH1]
Conjugations
Biotin
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1000)
  • ELISA
  • Functional Assay
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CD1D antibody was raised against rat CD1d-transduced M12.4.1. C3 cells.
Specificity
Recognizes rat CD1d, a glycoprotein expressed on cortical thymocytes, certain T-cell leukemias and various other antigen presenting cells. CD1d binds self and non-self glycolipids and presents them to T-cell receptors on natural killer cells. When activated, natural killer cells produce Th1 and Th2 cytokines. Clone WTH1 recognizes a different, non-overlapping epitope than clone WTH2 (, or ), and binds with high affinity to the mature CD1d heavy chain independently of beta-2-microglobulin. Clone WTH1 efficiently blocks rat and mouse invariant natural killer T cell (iNKT cell) response to a-GalCer (an antigen for iNKT cells) and has a slightly higher affinity to native CD1d than clone WTH2. Clone WTH1 cross reacts weakly with mouse tissue in IHC and western blotting, but reacts strongly with both rat and mouse antigens in flow cytometry and immunoprecipitation.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.02% sodium azide
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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